By ROBYN CHUTER

Obesity is bad to the brain. And the earlier in life you become obese, the worse for your long-term cognitive health.

Back in June 2021, I summarised three studies documenting the deleterious effects of excess body fat on the structure and function of the human brain, in Obesity: Bad to the Brain. I was reminded of this article when I came across a recently-published paper reporting some extremely concerning findings: young obese adults have elevated markers of a type of brain degeneration that are typically seen in much older people with Alzheimer’s disease. And these early signs of neural damage correlate not just with indicators of metabolic dysfunction, but also with low blood levels of choline.

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